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  • Eythrocyte-anti-PD1 conjugates in persons with advanced solid tumors resistant to anti-PD-1/PD-L1: preclinical characterization and results of a phase I trial

    Nie X*, Liu Y*, Yao X*, Huang Y, Chen Y, He X, Hao K, Yuan Y, Zheng J, Yang L, Feng Y#, Tingbo Liang#, Liu Yang# and Gao X#. 《Nature Cancer》 2026 Feb 20. doi: 10.1038/s43018-026-01125-2
    Commented by Nature Cancer
  • Single-dose erythrocyte–uricase conjugate with immunosuppressants induces durable immune tolerance to overcome uricase immunogenicity and treat gout

    Science Advances, 2025, Nov 21;11(47):eaea5196.doi: 10.1126/sciadv.aea5196.《Nature Reviews Rheumatology》 Epub 2025 Nov 19
    Highlighted by Nature Reviews Rheumatology
  • Single coadministration of erythrocyte-uricase conjugate and immunosuppressant induces durable immune tolerance for gout therapy

    Xiaoqian Nie*, Yuehua Liu*, Xingyun Yao*, Chaohao Wu, Xiaofei Gao# 《Science Advances》. 2025 Nov 21;11(47):eaea5196. doi: 10.1126/sciadv.aea5196. Epub 2025 Nov 19.
    PMID:41259518
  • DNA remnants in red blood cells enable early detection of cancer

    Sun H, Yao X, Jiao Y, Kong X, Han Y, Li Y, Ge J, Cao Y, Lu H, Wang P, Li J, Ding K and Gao X# 《Cell Research》. 2025 Aug;35(8):568-587. doi: 10.1038/s41422-025-01122-7. Epub 2025 May 9.
    PMID:40341742
  • BRAF inhibitors enhance erythropoiesis and treat anemia through paradoxical activation of MAPK signaling

    Wu, S., Deng, Y., Sun, H., Liu, X.……Lei, X., Tong, X.#, Gao, X.#, Lee, H.Y.# 《Signal Transduction and Targeted Therapy》. 2024 Dec 2;9(1):338. doi: 10.1038/s41392-024-02033-6.
    PMID:39617757
  • Lenalidomide-induced pure red cell aplasia is associated with elevated expression of MHC-I molecules on erythrocytes

    Hu Q, Liu Y, Yue Q, Zhou S, Jin X, Lin F, Huang XJ, Zhuang J#, Lu J#, Gao X#, Lee HY# 《Nature Communication》. 2024 Nov 22;15(1):10131. doi: 10.1038/s41467-024-54571-w.
    PMID:39578482
  • MED26-enriched condensates drive erythropoiesis through modulating transcription pausing

    Zhu S, Zhang X, Li M, Zhao X, Li N, Xie S, Yue Q, Li Y, Li D, Wu F, Zhang Z, Feng Z, Jia X, Deng Y, Hu Q, Yao X, Gao X#, Lee HY# 《eLife》.November 11, 2024,doi:10.7554/eLife.102023.1
    eLife.102023.1
  • Developing an erythrocyte‒MHC-I conjugate for cancer treatment

    Liu Y, Nie X, Yao X, Shou H, Yang Y, Tong X#, Lee HY#, Gao X# 《Cell Discovery》. 2024 Oct 1;10(1):99. doi: 10.1038/s41421-024-00713-9.
    PMID:39349449
  • Evolving insights into erythrocytes in synucleinopathies

    Yang Y, Nie X, Sun J, Gao X#, Zhang J# 《Trends in Neurosciences》. 2024 Sep;47(9):693-707. doi: 10.1016/j.tins.2024.06.005. Epub 2024 Jul 23.
    PMID:39043489
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